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YAP Polyclonal Antibody, 100ul[BT-AP09632] 3D Culture |disease:In B-cell leukemia (B-CLL) cell

SKU: 13037309466

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SEK141.00 SEK174.00

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YAP Polyclonal Antibody, 100ul[BT-AP09632] 3D Culture |disease:In B-cell leukemia (B-CLL) cellYAP1 encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Description

|disease:In B-cell leukemia (B-CLL) cell line| LB40 and EB308| can be found after heterogeneous chromosomal aberrations| such as internal deletions

Its product probably functions as an adhesion molecule and/or signaling receptor

including insulin

NFKB2 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p100 and generation of p52 by a cotranslational processing

YAP Polyclonal Antibody, 100ul[BT-AP09632] 3D Culture |disease:In B-cell leukemia (B-CLL) cellYAP1 encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

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